产品货号：
Z28519
中文名称：
TLR4抗体
英文名称：
Anti-TLR4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TLR4 Antibody |
| 指标别名 | ARMD10;CD284;hToll;TLR4;TOLL;toll like receptor 4 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | TLR4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human TLR4(50-68aa DNLPFSTKNLDLSFNPLRH). |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3 and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TLR4,Toll-like receptor 4,is a protein that in humans is encoded by the TLR4 gene.TLR 4 is a toll-like receptor.TLR4,the human homolog of Drosophila Toll,is a type I transmembrane protein with an extracellular domain consisting of a leucine-rich repeat region and an intracellular domain homologous to that of human interleukin-1 receptor.The TLR4 gene is mapped to chromosome 9q32-q33 by fluorescence in situ hybridization.It detects lipopolysaccharide from Gram-negative bacteria and is thus important in the activation of the innate immune system.The protein encoded by this gene is a member of the Toll-like receptor(TLR) family,which plays a fundamental role in pathogen recognition and activation of innate immunity.TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for the development of effective immunity. |
| Uniprot ID | O00206 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | toll-like receptor 4 |
| 蛋白名全称 | Toll-like receptor 4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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